API Impurities


impurities list of API molecules
165. 

Olanzapine

2-Methyl-4-(4-methyl-4-oxido-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine

174794-02-6

N-Oxide

166. 

Olanzapine

2-Methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine

161696-76-0

Piperazine imp

167. 

Olanzapine

1-(Chloromethyl)-1-methyl-4-(2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-yl)-piperazinium Chloride

719300-59-1

IMP-C

168. 

Oseltamivir

(3R,4R,5S)-Ethyl 4-(N-tert-butylacetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate hydrochloride

 

tert – Butyl acetamide
HCl Salt

169.

Oseltamivir

(3aR,4R,7aR)-6-(Ethoxycarbonyl)-3a,4,5,7a-tetrahydro-2,2-dimethylbenzo[d][1,3]dioxol-4-yl methanesulfonate

 

Mesyl shikmate imp

170.

Oseltamivir

Methyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate

 

WHO Imp-D (Methyl ester)

171. 

 

Paroxetin .HCl

4-((4-(4-Fluorophenyl)piperidin-3-yl)methoxy)benzene-1,2-diol

 

Diol imp

172.

 

Paroxetin

4-((4-(4-Fluorophenyl)piperidin-3-yl)methoxy)-2-methoxyphenol

 

Vaniline related metabolite

173. 

Paroxetin

5-((4-(4-Fluorophenyl)piperidin-3-yl)methoxy)-2-methoxyphenol

 

Isovaniline related metabolite

174. 

Paroxetin

((3S,4R)-4-(4-Fluorophenyl)
piperidin-3-yl)methanol

 

EP Imp-I

175. 

Paroxetin

((3S,4R)-1-Benzyl-4-(4-fluorophenyl)piperidin-3-yl)methanol

 

EP Imp-H

176. 

 

Paroxetin

4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine

1012886-75-7

USP RC-E (EP Imp-G)

177. 

 

Paliperidone

3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

761460-08-6

N-Oxide

178. 

 

Paliperidone

3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8-dihydro-2-methyl-6H-pyrido[1,2-a]pyrimidine-4,9-dione

1189516-65-1

Keto imp

179. 

 

Pantoprazole

5-(Difluoromethoxy)-1H-benzo[d]imidazole-2-thiol

97963-62-7

Benzimidazole

180. 

Pantoprazole

 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-1-oxido-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole

953787-55-8

Sulfone N-Oxide

181.

 

 

Pantoprazole

 

2-((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-5-(difluoromethoxy)-1-methyl-1H-benzo[d]imidazole

127780-16-9

 

Sulfone

182. 

Pantoprazole

2-((3,4-Dimethoxypyridin-2-yl)methylsulfinyl)-6-(difluoromethoxy)-1-methyl-1H-benzo[d]imidazole

 

IMP-D

183. 

Pantoprazole

2-((3,4-Dimethoxypyridin-2-yl)methylsulfinyl)-6-(difluoromethoxy)-1-methyl-1H-benzo[d]imidazole

 

IMP-F

184. 

Pioglitazone HCl

5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)-3-(2-(5-ethylpyridin-2-yl)ethyl)thiazolidine-2,4-dione

952188-00-0

Dimer Impurity

185. 

Prasugrel

5-Acetyl-4,5,6,7-tetrahydro
thieno[3,2-c]pyridin-2-yl acetate

 

Diacetyl impurity

186. 

Pyronaridine Tetraphosphate

4-(7-Chloro-2-methoxybenzo
[b][1,5]naphthyridin-10-ylamino)phenol

 

Aminoalcohol impurity

187. 

Pyronaridine Tetraphosphate

4-(7-chloro-2-methoxybenzo
[b][1,5]naphthyridin-10-ylamino)-2-((pyrrolidin-1-yl)methyl)phenol

 

Monosubstituted imp

188. 

Quetiapine

Quetiapine N-methyl impurity

 

N-methyl imp

189. 

 

Quetiapine Fumarate

 

 

Quetiapine piperzine dihydrochloride

 

190. 

Quetiapine Fumarate

2-[2-(4-Dibenzo [b,f][1,4]thia
zepin11-yl-1-iperazinyl)- ethanol(Quetiapine Hydroxy Impurity)

 

 

191. 

Quetiapine Fumarate

 

Dibenzo[b,f][1,4]thiazepine-11(10H)one(Quetiapine Related compound-G)

 

RC-G

192 

Quinapril

 

 

EP Imp-G

193. 

 

Quinapril

 

 

 

EP Imp-H