API Impurities


impurities list of API molecules
94. 

Desvenlafaxine

1-(1-(4-(benzyloxy)phenyl)-2-(dimethylamino)ethyl)cyclohexanol

93413-61-7

Dimethylamino
benzyloxyphenyl impurity

95. 

 

Desvenlafaxine

4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate

386750-22-7

Working standard

96. 

 

Isopropyl paratoluene sulfonate

2307-69-9

 

97. 

Escitalopram

3-Dimethylamino-1-propyl bromide

 

 

98. 

Efavirenz

((S,E)-6-Chloro-4-(2-Cyclopro
pylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one)

440124-96-9

Ethylene imp

99. 

 

Efavirenz

(S)-(-)-6-Chloro-4-(cyclopropyl
ethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one

154598-52-4

Enantiomer

100. 

 

Efavirenz

Efavirenz aminoalcohol methyl carbamate

211563-40-5

USP Amino alcohol methylcarbamate
(WHO-Imp-H)

101. 

Esomeprazole

(E)-2-(5-Methoxy-1H-benzo[d]imidazol-2-ylsulfinyl)-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-N,N-dimethylethenamine

 

Dimethyl imp

102.

Eszopiclone

2-(5-Chloropyridin-2-ylcarbamoyl)
benzoic acid

67232-57-9

EZP-I

103. 

Emtricitabine

5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione

 

Desamino imp

104. 

Emtricitabine

4-Amino-5-fluoro-1-((5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

 

Diastereomer

105. 

Enrofloxacin

1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoroquinolin-4(1H)-one

131775-99-0

Decarboxylated imp

106. 

Enrofloxacin

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid

85721-33-1

 

Ciprobase

107. 

Etoricoxib

(Z)-2-Chloro-3-(dimethylamino)acrylaldehyde

 

Aldehyde imp

108.

Etoricoxib

2-(6-(4-(Methylsulfonyl)
phenethyl)pyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine

 

 

 (Disulfonyl impurity)

109.

Etoricoxib

2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine

 

Deschloro imp

110. 

Eprosartan

2-((Thiophen-2-yl)methyl)malonic acid

4475-24-5

Diacid

111. 

Eprosartan

 

3-(Thiophen-2-yl)propionic acid

 

Decarboxylated imp

112. 

Eprosartan

4-((2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl)benzoic acid

 

Chloroimidazole
benzoic acid impurity

113. 

Fluindione

2-(4-Fluorophenyl)-2H-indene-1,3-dione

957-56-2

Working standard

114. 

Fluindione

(E)-3-(4-Fluorobenzylidene)
isobenzofuran-1(3H)-one

 

Benzylidene imp

115. 

Fluindione

2-(4-Methoxyphenyl)-2H-indene-1,3-dione

117-37-3

Methoxy imp

116. 

Gabapentine

 

2-Aza-spiro[4,5]decan-3-one

64744-50-9

 

Lactam

117. 

Gatifloxacin

1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid

 

Piperazine imp

118. 

Granisetron

 

 

N-Oxide

119. 

Iloperidone

Iloperidone N-oxide impurity

N/A

N-Oxide

120. 

Iloperidone

6-Fluoro-3-(piperidin-4-yl)benzo[d]isoxazole hydrochloride

84163-13-3

 

Benzisoxazole Impurity

121. 

Iloperidone

1-(4-(3-Bromopropoxy)-3-methoxyphenyl)ethanone

3245-49-6

Bromo impurity

122. 

Imatinib

4-(Chloromethyl)-N-[(3-(chloromethyl)(4-(pyridine-3-yl) pyrimid in-2-yl)amino)-4-methyl phenyl] benzamide(Imatinib

 

IMP-B

123. 

Imatinib

http://www.cachesyn.com/product_images/cst/CSTI099s.jpg

4-[(4-Methyl-4-oxido-piperazinyl) methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-3-yl)amino]phenyl]
benazamide

 

N-oxide

124. 

Imatinib

4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide

 

 

125. 

 

 

Imatinib

 

 


N-(4-Methyl-3-(4-methyl-3-yl-pyrimidin-2-ylamino)-phenyl)-4-chloromethylbenzamide