Imatinib

4-[(4-Methyl-1-Piperazinyl)
methyl]-N-[4-Methyl-3-[4-(3-Pyridinyl)-2-Pyrimidinyl] chloromethyl amino] phenyl]benzamide

Levofloxacin

Levofloxacin N-oxide

N/A

N-Oxide

Levofloxacin

Methyl 9,10-difluoro-3,5,6,7-tetrahydro-3-methyl-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ester

Levofloxacin

(R)-9,10-Difluoro-3,7-dihydro-3-methyl-7-oxo-2H-[1,4]oxazino
[2,3,4-ij]quinoline-6-carboxylic acid

R-Levo acid

Levofloxacin

(S)-3,7-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Desfluoro imp

Levofloxacin

(R)-10-(2-aminoethylamino)-9-fluoro-3,7-dihydro-3-methyl-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Ethylene diamine

Lansoprazole

(R)-9-fluoro-3,7-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

R-Isomer

Lansoprazole

 2-[[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]
methyl]sulfinyl]-1H-benzimidazole

213476-12-1

N-Oxide

Lansoprazole

2-((4-(2,2,2-Trifluoroethoxy)-3-methylpyridin-2-yl)methylthio)-1-methyl-1H-benzo[d]imidazole

N/A

SN1 impurity

Losartan

2-((4-Chloro-3-methylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]
imidazole

N/A

Chloro imp

Losartan

2-Butyl-5-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]
imidazole-4-methanol

860644-28-6

  IMP-C

Losartan

N1-Losartanyl Losartan

230971-71-8

EP Imp-L

Losartan

2-Butyl-1-[[2’-[2-[[2-butyl-4-chloro-1-[[2’-(2H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl][1,1’-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol

230971-72-9

EP Imp-M

Losartan

 O-Acetyl Losartan

1006062-27-6

EP Imp-J

Losartan

JP Imp-H

Loratadine

 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]
cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester

133284-74-9

IMP-A

Loratadine

4-(4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]
pyridin-11-ylidene)-1-piperidine
carboxylic Acid Ethyl Ester

165739-83-3

EP Imp-C (4-Chloro Loratadine)

Loratadine

4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one

133330-60-6

RC-E

Loratidine

31251-41-9

EP IMP-B

Lamotrigene

3-Amino-6-(2,3-dichlorophenyl)-1,2,4-trazin-5(4H)-one

252186-78-0

IMP-A

Lisinopril

(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-cyclohexylpropyl]
amino] hexanoyl]pyrrole-2-carboxylic acid

1132650-67-9

IMP-F

Lamivudine

(2R-cis)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid

173829-09-9

Carboxylic acid

Lamivudine

4-Amino-1-(2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one

Diastereomer

Lisinopril

2-Amino-4-phenylbutanoic acid

EP Imp-A

Levetiracetam

Methyl 2-(2-oxopyrrolidin-1-yl)
butanoate

Methyl ester

Linazolid

(5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone(Linazolid -A)

IMP-A

Linazolid

N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-ethane thioamide(linazolid-B)

IMP-B

Linazolid

(-)-(S)-5-(Aminomethyl)-3-(3-fluoro-4-morpholinophenyl)
oxazolidin-2-one (Linazolid-C)

IMP-C

Modafinil

2-(Benzhydrylsulfinyl)acetic acid

63547-24-0

Acid (EP Imp-A)

Modafinil

Methyl 2-(benzhydryl
sulfinyl)acetate

713134-72-6

Ester (EP Imp-C)

Nabumetone

4-(2-Methoxynaphthalen-6-yl)butan-2-ol

65726-24-1

Hydroxy Imp

Naproxen

1-(2-Methoxynaphthalen-1-yl)ethanone

Isomer Acetyl yara yara Impurity

Naproxen

1-(2-Methoxynaphthalen-6-yl)ethanone

Acetyl yara yara imp

Norfloxacin

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-5-(piperazin-1-yl)quinoline-3-carboxylic acid

Isomer impurity

Nelfinavir

 ((3S,4aS,8aS)-N-Tert-Butyl-2-[(2R,3R)-2-hydroxy-3-(3-hydroxy-2-methylbenzamido)-4-(phenylsulfinyl)butyl]decahydroisoquinoline-3-carboxamide)

1041389-28-9

Sulfoxide imp
Or
IMP-B

Nelfinavir

(3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)
amino]-4-(phenylsulfonyl)butyl]-3-isoquinolinecarboxamide

1041389-29-0

Sulfone imp or
IMP-C

Omeprazole

6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

176219-04-8

N-oxide

Omeprazole

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfonyl]-
1H-benzimidazole

Sulfone N-oxide

Oxcarbazepine

Carbamazepine Impurity